Related Experiment Video
Updated: Jul 13, 2026

Adjunctive Diode Laser Therapy and Probiotic Lactobacillus Therapy in the Treatment of Periodontitis and Peri-Implant Disease
Published on: May 9, 2022
Beneficial effects of periodontal treatment on metabolic control of hypercholesterolemia
S Gul Oz1, Ozlem Fentoglu, Alpaslan Kilicarslan
1Hacettepe University Faculty of Medicine, Department of Internal Medicine, Ankara, Turkey. irem8886@yahoo.com
Background:
The authors aimed to evaluate whether local periodontal therapy may influence plasma lipid levels in patients with periodontitis.
Methods:
Fifty patients (31 females and 19 males, age 36-66 yr) were randomly assigned to the treatment and control groups. Lipid profile and dental variables were measured at baseline and at the end of the study in both groups.
Results:
In the third month, there was a significant decrease in total and low density lipoprotein (LDL) cholesterol levels of the treatment group compared with baseline values. Also, the reduction in bleeding on probing, pocket depth, attachment loss, plaque index and gingival index were statistically significant in the treatment group.
Conclusions:
The present study indicates that periodontitis causes changes in total and LDL cholesterol levels and local periodontal treatment resulted in a significant decrease in these markers. These results suggest a potential effect of periodontitis-driven systemic inflammation on lipid metabolism.
Related Concept Videos
Atherosclerosis III: Management
Lipid-Lowering Drugs: Statins and Miscellaneous Agents
Cholesterol: Significance and Regulation
Considering cholesterol and...
The Oral Microbiota
Coronary Artery Disease IV: Preventive Measures
Diabetes: Management and Pharmacotherapy
Insulin remains the cornerstone of treatment for most patients with type 1 and many...