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Updated: Jul 13, 2026

A 3D Organotypic Melanoma Spheroid Skin Model
Published on: May 18, 2018
Late-onset Ito's nevus: an uncommon acquired dermal melanocytosis
Javier Mataix1, Norberto López, Rosario Haro
1Department of Dermatology, Fundación Jiménez Díaz, Universidad Autónoma, Madrid, Spain.
Abstract:
Dermal melanocytoses comprise a variety of congenital and acquired conditions characterized by a sparse population of intradermal dendritic, variably pigmented, spindle-shaped melanocytes. While Mongolian spot, Ota's and Ito's nevi are usually present at birth or appear around puberty; acquired dermal melanocytoses that appear in adult life are extremely rare. They include the facial lesions of acquired bilateral nevus of Ota-like macules, also named Hori's nevus, and the acquired unilateral nevus of Ota, also known as Sun's nevus. Uncommon extrafacial examples of acquired dermal melanocytoses include lesions involving upper extremities, wrist, back, lower extremities and dorsal aspects of the hands and feet. They are more prevalent among Asian women. In general, dermal melanocytoses are rare lesions in Caucasian patients and acquired variants are exceedingly uncommon. We report a rare example of acquired Ito's nevus that appeared in a Caucasian elderly woman and review the literature about acquired dermal melanocytoses.
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