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Updated: Jul 13, 2026

Midface Hypoplasia and Cranial Base Morphology in Syndromic Craniosynostosis: A Comparative Analysis Study Using a Predictive Regression Model
Published on: November 4, 2025
Orthodontic status and head morphology in young males
1Institute and Museum of Anthropology, Moscow State University, Moscow, Russian Federation. nadezda@list.ru
Unlabelled:
Complete anthropometrical data on a sample of 111 Russian males aged 20.0+/-2.3 years were obtained to investigate craniofacial morphology according to individual orthodontic status (OS). Subsample analyses were performed, using a variety of grouping factors. a) 1-spacing on both dental arches; 2-absence of crowding, spacing, rotation, or displacement of teeth on both dental arches; 3-crowding on both dental arches; b) 1-spacing on mandible; 2-absence of crowding, spacing, rotation, or displacement of teeth on mandible; 3-crowding on mandible; c) 1-spacing on maxilla; 2-absence of crowding, spacing, rotation, or displacement of teeth on maxilla; 3-crowding on maxilla. Wilks' Lambdas were found to be 0.29 to 0.59; all were significant.
Conclusions:
1. Significant positive and negative correlations were found between craniofacial measurements and an individual's OS. 2. Measurements exhibited statistically significant differences between the groups with different OS at the p<0.05 level and some at p<0.01. 3. Using forward stepwise discriminant analysis, a high difference in craniofacial architecture between the groups with different OS was found. Canonical discriminant analysis indicates the face pattern connected to crowding: relatively high medial vertical mandible height in combination with a vertically long and narrow face; to spacing: a wide face with wide nose and high upper lip is combined with shortened medial vertical mandible height. 4. Depending upon the grouping factor, 10 to 12 variables were chosen in the canonical discriminant model. Classification functions and means of canonical roots were calculated; morphological interpretations of canonical roots were performed. 5. Definitive OS is a complicated product of interaction during the ontogenesis of jaws between the time of teeth eruption and the growth of two growth fields (alveolar and corpus) under the simultaneous influence of hormonal status and the chronological age of the individual.
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