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Local Anesthetics: Differential Sensitivity of Nerve Fibers01:24

Local Anesthetics: Differential Sensitivity of Nerve Fibers

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Measurement & Analysis of the Temporal Discrimination Threshold Applied to Cervical Dystonia
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Individual variability in the peripheral and core interthreshold zones.

Naoshi Kakitsuba1, Igor B Mekjavic, Tetsuo Katsuura

  • 1Department of Environment and Technology, School of Science and Technology, Meijo University, Nagoya, Aichi, Japan. naoshi@ccmfs.meijo-u.ac.jp

Journal of Physiological Anthropology
|July 21, 2007
PubMed
Summary

This study examined individual differences in body temperature regulation during shivering and sweating. Results show personal variability in core and peripheral temperature thresholds, with adiposity playing a significant role.

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Area of Science:

  • Human physiology
  • Thermoregulation
  • Environmental physiology

Background:

  • Understanding human thermoregulation is crucial for various fields, including sports science, occupational health, and clinical medicine.
  • Individual variability in physiological responses to thermal stress is well-documented but requires further investigation regarding specific thresholds.

Purpose of the Study:

  • To investigate subject variability in peripheral and core temperature thresholds for the onset of shivering and sweating.
  • To establish the peripheral and core interthreshold zones in healthy young males.

Main Methods:

  • Nine healthy young males underwent three trials involving exposure to different ambient temperatures and exercise while wearing a water-perfused suit.
  • Skin temperature (Tsk) and rectal temperature (Tre) were monitored, alongside oxygen uptake to determine the onset of shivering.
  • Thermoregulatory responses were assessed under conditions isolating peripheral and core temperature influences.

Main Results:

  • Individual variability was observed in both peripheral and core interthreshold zones.
  • A strong proportional correlation (r=0.87) was found between the peripheral and core interthreshold zones.
  • Adiposity demonstrated a relatively higher contribution to these zones compared to other non-thermal factors like height and weight.

Conclusions:

  • Significant individual differences exist in the body's temperature regulation thresholds.
  • Adiposity is a key factor influencing thermoregulatory responses, more so than anthropometric measures.
  • The findings provide valuable insights into personalized thermoregulation and its influencing factors.