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Several body functions deteriorate with age. The external signs of aging are easily identifiable. For example, the skin becomes dry, less elastic, and thins out, forming wrinkles. The skin of the face begins to appear looser due to a decrease in the levels of elastic and collagen fibers in the connective tissue. Additionally, melanin production in the hair follicle decreases with age, resulting in gray hair. Moreover, the senses of sight and hearing decline, so glasses and hearing aids may...

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Related Experiment Videos

Exogenous factors in skin aging.

Marina Landau¹

¹Dermatology, Wolfson Medical Center, Holon, Israel.

Current Problems in Dermatology

|July 21, 2007

Summary

Skin aging results from genetic and environmental factors like sun exposure and smoking. This review details extrinsic skin aging features and the underlying biochemical processes.

Area of Science:

Dermatology
Molecular Biology
Biochemistry

Background:

Skin aging is influenced by intrinsic (genetic) and extrinsic (environmental) factors.
Extrinsic aging, unlike intrinsic aging, is not inevitable and presents distinct features.
Sun exposure and smoking are primary environmental contributors to skin aging.

Purpose of the Study:

To review the distinct morphological and histological features of extrinsic skin aging.
To elucidate the biochemical mechanisms underlying environmentally induced skin aging.
To summarize the skin's defense mechanisms against aging and their decline over time.

Main Methods:

Review of scientific literature on skin aging.
Analysis of molecular biology research on exogenous aging factors.

Related Experiment Videos

Comparison of intrinsic versus extrinsic skin aging characteristics.

Main Results:

Extrinsic aging exhibits specific morphological and histological changes.
Molecular biology advances reveal biochemical pathways affected by environmental factors.
The skin's natural protective mechanisms diminish with age, increasing susceptibility to extrinsic aging.

Conclusions:

Extrinsic factors significantly impact skin aging, with distinct characteristics from intrinsic aging.
Understanding the biochemical steps of extrinsic aging is crucial for developing interventions.
The decline in the skin's defense efficacy necessitates further research into mitigating environmental damage.