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Teratogenicity studies of a new potent tetanus vaccine in rabbit (Oryctolagus cuniculus)
N Sethi1, R K Srivastava, R K Singh
1Division of Toxicology, Central Drug Research Institute, Lucknow, India.
Biomedical and Environmental Sciences : BES
|September 1, 1991
Abstract:
Glaxo Laboratories, Bombay, have prepared a potent tetanus vaccine of 250 Lf as a substitute of the previous 5 Lf tetanus vaccine. The safety evaluation of the vaccine has been reported, but the teratogenic potential was not studied. In the experiment reported herein we have studied the teratogenic action of the vaccine in the progeny of rabbits. No congenital anomalies were observed.