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Related Experiment Video

Updated: Jul 13, 2026

A New Technique for Quantitative Analysis of Hair Loss in Mice Using Grayscale Analysis

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Published on: March 9, 2015

Nail changes in alopecia areata: incidence and pattern.

V Gandhi¹, M C Baruah, S N Bhattacharaya

¹Dept. of Dermatology & STD, GTB Hospital, Delhi.

Indian Journal of Dermatology, Venereology and Leprology

|July 24, 2007

Summary

Nail abnormalities are common in alopecia areata patients, affecting 44%. Superficial pits were the most frequent finding. These nail changes may signal a more severe form of alopecia areata.

Area of Science:

Dermatology
Trichology

Background:

Alopecia areata is an autoimmune condition causing hair loss.
Nail involvement in alopecia areata is recognized but not fully characterized.

Purpose of the Study:

To investigate the prevalence and types of nail abnormalities in patients with alopecia areata.
To determine if nail changes correlate with disease severity or subtype.

Main Methods:

Prospective examination of 100 consecutive patients diagnosed with alopecia areata.
Systematic documentation of all observed nail abnormalities.
Correlation analysis of nail changes with alopecia areata subtype and clinical presentation.

Main Results:

44% of patients exhibited nail abnormalities.

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The multifocal variety of alopecia areata showed the highest incidence of nail changes (68%).

Superficial pitting was the most common abnormality, observed in 64% of affected patients.

Conclusions:

Nail abnormalities are a frequent finding in alopecia areata.
The presence and severity of nail changes may serve as indicators of a more severe and treatment-resistant disease course.