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Dermoscopy Aids in the Diagnosis of Discoid Lupus Erythematosus

Dermoscopy Aids in the Diagnosis of Discoid Lupus Erythematosus

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Oral lesions in leprosy.

A Costa¹, J Nery, M Oliveira

¹Department of Infectious and Parasitic Diseases, HUCFF-UFRJ and School of Medicine, Federal University of Rio de Janeiro.

Indian Journal of Dermatology, Venereology and Leprology

|July 24, 2007

Summary

Leprosy can manifest in the mouth, particularly in lepromatous leprosy. Early detection and treatment of oral lesions are crucial for preventing disease spread and managing leprosy reactions.

Area of Science:

Oral medicine
Infectious diseases
Dermatology

Background:

Leprotic oral lesions are more common in lepromatous leprosy, indicating a late stage.
Oral lesions in leprosy have significant epidemiological importance as a source of infection.

Purpose of the Study:

To investigate the prevalence and characteristics of oral lesions in leprosy patients.
To correlate clinical findings with histopathological results in leprosy-associated oral manifestations.

Main Methods:

Examination of leprosy patients for oral lesions.
Biopsies of buccal mucosa and oral lesions for H&E and Wade staining.

Main Results:

Oral lesions were identified in 26 patients (11 lepromatous, 14 borderline, 1 tuberculoid).

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Cutaneous Leishmaniasis in the Dorsal Skin of Hamsters: a Useful Model for the Screening of Antileishmanial Drugs

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Clinical manifestations included enanthem and palatal infiltration; viable bacilli were found in two lepromatous patients.

Oral clinical alterations were present in 69% of patients, with 50% showing histopathological changes in clinically unaffected areas.

Conclusions:

Reduced incidence of oral changes may be due to early leprosy treatment.
Oral infection can precipitate and sustain leprosy reactions and serve as an infection source.
Oral disease in leprosy warrants attention for early detection and treatment to prevent disease transmission.