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Brain Abscess l: Introduction

A brain abscess is a focal, intracerebral infection characterized by a localized collection of pus within the brain parenchyma, resulting from microbial invasion and the body’s inflammatory response. It progresses through stages: early and late cerebritis, followed by early and late capsule formation, reflecting tissue destruction, immune response, and eventual encapsulation.Etiology and PathogenesisCausative organisms vary with source and host factors, often involving polymicrobial infections,...
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Preparation of Agar Bead Embedded Mycobacterium abscessus to Inoculate Immunocompetent Mice Intratracheally
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Injection site abscess due to Mycobacterium fortuitum: a case report.

D R G Devi1, V A Indumathi, S Indira

  • 1Department of Microbiology, MS Ramaiah Medical Teaching Hospital, Bangalore - 560 054, Karnataka, India.

Indian Journal of Medical Microbiology
|July 24, 2007
PubMed
Summary

Unusual mycobacteria can cause injection site abscesses, even in children. Prompt acid-fast bacilli testing is crucial for diagnosing these rare infections.

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Area of Science:

  • Infectious Diseases
  • Microbiology
  • Pediatrics

Background:

  • Injection abscesses are iatrogenic infections resulting from contaminated injectables or poor sterilization.
  • Commonly identified pathogens include Pseudomonas, Klebsiella, E. coli, and S. aureus.
  • Rarely, rapidly growing non-tuberculous mycobacteria (NTM) can cause these abscesses.

Purpose of the Study:

  • To highlight the potential for non-tuberculous mycobacteria (NTM) to cause injection abscesses.
  • To emphasize the importance of specific diagnostic methods for identifying unusual pathogens.
  • To report a case of gluteal abscess in a child caused by an unknown preparation.

Main Methods:

  • Case report of a three-year-old child with a gluteal abscess.
  • Review of causative agents of injection abscesses.
  • Emphasis on the diagnostic utility of acid-fast bacilli (AFB) smear and culture for pus specimens.

Main Results:

  • The child presented with a gluteal abscess after an intramuscular injection.
  • The causative agent was suspected to be an unusual organism, potentially NTM.
  • Standard cultures may miss NTM without specific AFB testing.

Conclusions:

  • Non-tuberculous mycobacteria (NTM) should be considered in the differential diagnosis of injection abscesses, especially when standard cultures are negative or atypical.
  • Acid-fast bacilli (AFB) smear and culture are essential for the early and accurate diagnosis of mycobacterial infections.
  • Prompt diagnosis and appropriate treatment are critical to manage these iatrogenic infections effectively.