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Updated: Jul 13, 2026

Repressing Gene Transcription by Redirecting Cellular Machinery with Chemical Epigenetic Modifiers
Published on: September 20, 2018
Actin-related proteins in chromatin-level control of the cell cycle and developmental transitions
Richard B Meagher1, Muthugapatti K Kandasamy, Roger B Deal
1Department of Genetics, University of Georgia, Athens, GA 30602, USA. meagher@uga.edu <meagher@uga.edu>
Abstract:
Regulating developmental transitions, cell proliferation and cell death through differential gene expression is essential to the ontogeny of all multicellular organisms. Chromatin remodeling is an active process that is necessary for managing the genome-wide suppression of gene activities resulting from DNA compaction. Recent data in plants suggest a general theme, whereby chromatin remodeling complexes containing nuclear actin-related proteins (ARPs) potentiate the activities of crucial regulatory genes involved in plant growth and development, in addition to their basal activities on a much larger set of genes.
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