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Myocardial infarction in adolescents
William T Mahle1, Robert M Campbell, Jennifer Favaloro-Sabatier
1Sibley Heart Center, Children's Healthcare of Atlanta and Department of Pediatrics, Emory University School of Medicine, Atlanta, GA 30322-1062, USA. wmahle@emory.edu
The Journal of Pediatrics
|July 24, 2007
Summary
Acute myocardial infarction (AMI) is very rare in adolescents, predominantly affecting males. While survival rates are high, associated factors include substance abuse and smoking.
Area of Science:
- Cardiology
- Pediatric Cardiology
- Epidemiology
Background:
- Acute myocardial infarction (AMI) is uncommon in adolescents.
- Understanding the incidence and risk factors for AMI in this demographic is crucial.
Purpose of the Study:
- To determine the incidence, characteristics, and outcomes of acute myocardial infarction (AMI) in adolescents aged 13 to 18 years.
- To identify patient profiles and risk factors associated with adolescent AMI.
Main Methods:
- Analysis of data from the Nationwide Inpatient Sample (1998-2001).
- Exclusion of patients with primary cardiomyopathies, congenital heart lesions, or prior heart transplantation.
- Calculation of AMI incidence per year and per patient-year.
Main Results:
- Estimated incidence of adolescent AMI admissions is 157 per year (6.6 per 1 million patient-years).
- AMI predominantly affects males (80%); substance abuse and smoking are significantly higher in affected adolescents.
- Hospital mortality was low (0.8%), with uncommon need for coronary angiography or bypass surgery.
Conclusions:
- Acute myocardial infarction (AMI) is an extremely rare condition in adolescents.
- Risk factors include male sex, substance abuse, and tobacco use.
- Hospital survival for adolescent AMI is excellent, with limited need for invasive cardiac interventions.
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