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Related Experiment Videos

HIV and banked fascia lata.

E H Bedrossian1

  • 1Wills Eye Hospital Fascia Lata Bank, Department of Ophthalmic Plastic Surgery, Philadelphia, Pennsylvania 19107.

Ophthalmic Plastic and Reconstructive Surgery
|January 11, 1991
PubMed
Summary

Banked irradiated fascia lata is safe for ophthalmic plastic surgery. Strict screening and sterilization methods prevent communicable disease transmission, including human immunodeficiency virus (HIV), in donated human tissue.

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Area of Science:

  • Ophthalmology
  • Tissue banking
  • Infectious disease control

Background:

  • Concerns about communicable disease transmission via donor tissue have risen.
  • Ophthalmic plastic surgeons utilize banked homologous irradiated fascia lata.
  • The Wills Eye Hospital Fascia Lata Bank has distributed 959 tissue samples over 3 years.

Purpose of the Study:

  • To evaluate the safety of banked irradiated homologous fascia lata.
  • To assess the risk of disease transmission from donor tissue.
  • To report on the efficacy of safety protocols in tissue banking.

Main Methods:

  • Implementation of strict donor selection criteria.
  • Comprehensive antibody testing for HIV, RPR, and HbsAg.
  • Sterilization using heat treatment and 4 million rads of cobalt-60 gamma radiation.

Main Results:

  • No reported cases of HIV transmission through implanted fascia lata.
  • Extensive safety measures are in place for tissue banking.
  • Successful distribution of tissue samples nationwide.

Conclusions:

  • Banked irradiated homologous fascia lata is a safe option for ophthalmic plastic surgery.
  • Current safety protocols effectively mitigate disease transmission risks.
  • Continued vigilance in tissue banking practices is essential.

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