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Published on: February 20, 2020

Relative value of 25(OH)D and 1,25(OH)2D measurements

Paul Lips1

  • 1Department of Endocrinology, VU University Medical Center, Amsterdam, The Netherlands. p.lips@vumc.nl

Journal of Bone and Mineral Research : the Official Journal of the American Society for Bone and Mineral Research
|July 25, 2007
PubMed
Abstract

No abstract available in PubMed .

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Volume of Distribution01:20

Volume of Distribution

The apparent volume of distribution (Vd) is a crucial pharmacokinetic parameter representing the hypothetical body fluid volume into which a drug disperses. It is calculated based on the total amount of drug in the body (estimated from the administered dose and bioavailability) divided by the plasma drug concentration. The total amount of drug in the body does not directly refer to the dose given but is derived by accounting for absorption, distribution, metabolism, and excretion processes.