Computational prediction of host-pathogen protein-protein interactions

Matthew D Dyer1, T M Murali, Bruno W Sobral

  • 1Genetics, Bioinformatics and Computational Biology Program, Virginia Polytechnic Institute and State University, Blacksburg, VA 24061, USA. dyermd@vbi.vt.edu

Summary

This study introduces a computational method to predict host-pathogen protein-protein interactions (PPIs) by integrating intra-species PPIs and protein domains. The approach identifies potential therapeutic targets for infectious diseases like malaria.

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