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Published on: February 10, 2023
Venous thromboembolism in the outpatient setting
Frederick A Spencer1, Darleen Lessard, Cathy Emery
1Department of Medicine, University of Massachusetts Medical School, Worcester, USA. fspence@mcmaster.ca
Most venous thromboembolism (VTE) events occur after hospital discharge, not during hospitalization. Improving in-hospital VTE prophylaxis and exploring extended prophylaxis post-discharge are crucial for reducing outpatient VTE incidence.
Area of Science:
- Medical research
- Public health
- Clinical epidemiology
Background:
- Venous thromboembolism (VTE) prophylaxis is often focused on hospitalized patients.
- However, a significant portion of VTE events occur in the outpatient setting.
- This study investigates outpatient VTE occurrence, risk factors, and prophylaxis patterns.
Purpose of the Study:
- To determine the frequency of VTE in the outpatient setting.
- To characterize prevalent VTE risk factors among outpatients.
- To assess the utilization of VTE prophylaxis in patients who later develop outpatient VTE.
Main Methods:
- Retrospective review of medical records for residents of the Worcester metropolitan area.
- Inclusion criteria: International Classification of Diseases, Ninth Revision codes consistent with possible VTE.
- Data collected for 1999, 2001, and 2003, validated by trained abstractors.
Main Results:
- A total of 1897 VTE cases were confirmed.
- 73.7% of VTEs occurred in the outpatient setting.
- Of those with recent hospitalization, 67.0% developed VTE within 1 month post-discharge; less than half received prophylaxis during hospitalization.
Conclusions:
- VTE diagnoses are more common in the 3 months following hospitalization than during the hospital stay itself.
- Enhanced in-hospital VTE prophylaxis may reduce outpatient VTE rates.
- Extended VTE prophylaxis after hospital discharge warrants further investigation due to shortened hospital stays.
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