Related Experiment Video
Updated: Jul 13, 2026

Establishment of a Modified Ferric Chloride-Induced Superior Sagittal Sinus Thrombosis
Published on: December 30, 2025
Stroke complicating congenital sick sinus syndrome
R Lehmann1, G Groenefeld, C W Israel
1Department of Medicine, Division of Cardiology/Clinical Electrophysiology, J.W. Goethe University Hospital, Frankfurt, Germany.
Congenital sick sinus syndrome can lead to atrial fibrillation and stroke decades later. Pacemaker and anticoagulation manage symptoms, but asymptomatic atrial fibrillation recurrences persist.
Area of Science:
- Cardiology
- Electrophysiology
- Neurology
Background:
- Congenital sick sinus syndrome (SSS) is a rare cardiac condition affecting heart rhythm.
- Early diagnosis and management are crucial for long-term patient outcomes.
Observation:
- A 34-year-old patient, diagnosed with congenital SSS at age 11, presented with atrial fibrillation and embolic stroke.
- This occurred 23 years after the initial SSS diagnosis.
Findings:
- Treatment involved a dual-chamber pacemaker and oral anticoagulation.
- Pacemaker diagnostics revealed persistent, asymptomatic paroxysmal atrial fibrillation episodes despite treatment.
Implications:
- Long-term monitoring is essential for patients with congenital SSS, even after initial treatment.
- Asymptomatic atrial fibrillation poses a continued embolic risk in these patients.
- This case highlights the complex, long-term management challenges of congenital SSS.
More Related Videos
08:42Cox-Maze IV Procedure Concomitant with Valvular Surgery In Situs Inversus Dextrocardia: A Single-Center Experience in China
Published on: February 11, 2022
09:20Microelectrode Array Recording of Sinoatrial Node Firing Rate to Identify Intrinsic Cardiac Pacemaking Defects in Mice
Published on: July 5, 2021
Related Concept Videos
Mitral Stenosis I: Introduction
ECG Interpretation of Arrhythmias I: Sinus Arrhythmias
Types of Arrhythmias
Sinus Node Arrhythmias
Sinus Bradycardia: Originating from the sinoatrial (SA) node, sinus bradycardia involves slower impulses, resulting in a heart rate of less than 60 beats per minute (bpm). Causes include sleep, vagal stimulation, beta-blockers, hypothyroidism, and...
Overview of Systemic Veins
The coronary sinus, the heart's principal vein, resides in the coronary sulcus on the heart's posterior aspect. This broad venous channel receives nearly all venous blood from the myocardium, the heart muscle. It is fed by three primary veins: the great cardiac vein, the middle...
Cardiomyopathy III: Hypertrophic Cardiomyopathy
Mitral Stenosis II: Clinical features and Diagnostic Tests
Mitral Stenosis III: Medical Management