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Updated: Jul 13, 2026

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A Modified Surgical Technique for Kidney Transplantation in Mice
Published on: July 22, 2022
[Double kidney transplantation--a method to increase the donor pool].
Zsolt Csapó1, Bence Forgács, D Barry Kahan
1University of Texas Medical School, Houston, Texas, USA.
Magyar Sebeszet
|July 26, 2007
Summary
Double kidney transplantation using carefully selected, previously rejected organs is a viable strategy to increase organ availability. This approach successfully improved kidney function and eliminated the need for dialysis in recipients.
Area of Science:
- Nephrology
- Transplantation Surgery
- Immunology
Context:
- Increasing demand for kidney transplants exceeds donor availability.
- Marginal donor kidneys require specific strategies for optimal outcomes.
- Utilizing extended criteria or previously refused organs is necessary to expand the donor pool.
Purpose:
- To evaluate the efficacy of double kidney transplantation using organs refused by local services.
- To assess the outcomes of transplanting both kidneys from a single donor into one recipient.
- To determine if previously rejected kidneys can be successfully utilized through this technique.
Summary:
- Five double kidney transplantations were performed using organs refused by local transplant services.
- Both kidneys were transplanted retroperitoneally on the same side.
- Recipients experienced immediate kidney function, with significant improvements in serum creatinine and Glomerular Filtration Rate (GFR).
- Two patients had acute rejection episodes, but all avoided long-term dialysis during the two-year follow-up.
Impact:
- Double kidney transplantation offers an acceptable solution for expanding the donor pool.
- Cautious selection of previously rejected kidneys can lead to successful transplant outcomes.
- This technique provides a valuable option for patients on kidney transplant waiting lists.
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