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T2-selective magnetization preparation pulses.

Logi Vidarsson1, Charles Cunningham, Garry E Gold

  • 1Department of Medical Imaging and Medical Biophysics, The Hospital for Sick Children, University of Toronto, ON, Canada. logi@sickkids.ca

IEEE Transactions on Medical Imaging
|July 26, 2007
PubMed
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This study introduces a novel method for designing T2-selective preparation pulses using a modified Shinnar-Le-Roux transform. The new technique effectively suppresses long T2 signal in MRI scans, demonstrating robustness against field inhomogeneities.

Area of Science:

  • Magnetic Resonance Imaging
  • Pulse Sequence Design
  • Biomedical Engineering

Background:

  • Designing effective T2-selective preparation pulses is crucial for advanced MRI techniques.
  • Existing methods may involve complex trade-offs and limitations in achieving desired signal contrast.

Purpose of the Study:

  • To present and evaluate a new, direct method for designing T2-selective preparation pulses.
  • To simplify the analysis of design trade-offs in T2-selective pulse development.

Main Methods:

  • Utilized a modified Shinnar-Le-Roux (SLR) transform to convert pulse design into polynomial design.
  • Developed a short-T2-selective magnetization preparation pulse using this polynomial approach.
  • Evaluated the pulse with Bloch simulations, phantom scans, and in vivo imaging using a 2D Fourier transform (2DFT) multislice gradient echo sequence.

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Main Results:

  • Phantom scans demonstrated effective signal suppression of long T2 species.
  • In vivo images corroborated the good suppression of long T2 signals.
  • Bloch simulations confirmed pulse robustness against B0 (±150 Hz) and B1 (±10%) inhomogeneities.

Conclusions:

  • The modified SLR transform offers a direct and effective approach for designing T2-selective preparation pulses.
  • The designed pulse provides excellent long T2 signal suppression, crucial for various MRI applications.
  • The method's robustness ensures reliable performance in the presence of common MRI field imperfections.