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Effect of heart rate on tissue Doppler measures of diastolic function

Andrew T Burns1, Kim A Connelly, Andre La Gerche

  • 1Cardiac Investigation Unit, St. Vincent's Hospital, Melbourne, Victoria, Australia. andrew.burns@svhm.org.au

Echocardiography (Mount Kisco, N.Y.)
|July 27, 2007
PubMed

Insights

Heart rate significantly impacts diastolic function measurements, specifically tissue Doppler imaging (TDI) parameters like mitral annular velocities. These findings suggest a need to adjust TDI measurements for heart rate in clinical practice.

Area of Science:

  • Cardiology
  • Echocardiography
  • Diastolic Function

Background:

  • The independent effect of heart rate (HR) on diastolic function parameters, particularly mitral annular velocities measured by tissue Doppler imaging (TDI), is not well understood.
  • Understanding this relationship is crucial for accurate echocardiographic assessment.

Purpose of the Study:

  • To investigate the independent effect of varying heart rates (HR) on key diastolic function parameters.
  • To specifically examine the impact of accelerated HR on mitral inflow and mitral annular velocities measured by TDI.

Main Methods:

  • Sixteen patients with dual-chamber pacemakers underwent echocardiography during atrial pacing at baseline and accelerated HRs.
  • Mitral inflow velocities, annular tissue Doppler velocities, and systolic strain parameters were assessed and compared.

Main Results:

  • Systolic function parameters remained unaffected by increased HR.
  • A significant decrease in early mitral inflow (E) wave and early mitral annular (E') velocities was observed with accelerated HR.
  • A significant increase in mitral inflow A wave and late mitral annular (A') velocities occurred at higher HRs.

Conclusions:

  • Changes in heart rate exert significant, previously unrecognized effects on tissue Doppler parameters of diastolic function.
  • Further research is necessary to determine if tissue Doppler-derived annular velocities require HR correction for clinical application.
Abstract

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