Related Experiment Video
Updated: Jul 13, 2026

Rapid Antimicrobial Susceptibility Testing by Stimulated Raman Scattering Imaging of Deuterium Incorporation in a Single Bacterium
Published on: February 14, 2022
[Streptococcal pharyngitis in the pediatric emergency department: value and impact of rapid antigen detection test]
N Buchbinder1, A Benzdira, A Belgaïd
1Service des urgences pédiatriques, hôpital Flaubert, groupe hospitalier, 55 bis, rue Gustave-Flaubert, 76600 Le Havre, France.
Insights
The rapid streptococcus test strip effectively reduces antibiotic prescriptions in pediatric emergency settings. This diagnostic tool is a realistic option for improving antibiotic targeting in children with pharyngitis.
Area of Science:
- Pediatric infectious diseases
- Microbiology
- Clinical diagnostics
Context:
- The French Health Agency (Afssaps) recommends rapid streptococcus test strips for targeted antibiotic prescribing.
- Antibiotic overuse is a significant public health concern, particularly in pediatric care.
Purpose:
- To evaluate the systematic implementation of rapid streptococcus test strips in a pediatric emergency department.
- To assess the impact of rapid testing on antibiotic prescription patterns for acute pharyngitis.
Summary:
- A study involving 2,144 children with acute pharyngitis compared rapid test strip results with laboratory cultures.
- The rapid test demonstrated a sensitivity of 77% and specificity of 82%.
- Antibiotic prescriptions decreased significantly, with 70% of pharyngitis cases not receiving antibiotics.
Impact:
- Widespread use of rapid streptococcus test strips significantly impacts antibiotic prescribing practices.
- The rapid test is a feasible and effective diagnostic tool for pediatric emergency units, aiding in judicious antibiotic use.
Unlabelled:
The French Health Agency (Afssaps) recommands the resort to the streptocoque rapid test strip for a better targetting of antibiotics prescription.
Objectives:
To evaluate the systematic use of the test in a pediatric emergengy department.
Methods:
Comparison of results of the test to the laboratory cultures. Our study took place between January and December 2004. Two thousand one hundred (and) forty-four children with acute pharyngitis have been included (mean age: 4.8+/-3.6 years).
Results:
Group A streptococcus was involved in 57 pharyngitis (26%). Mean age of children with positive culture was 7+/-3 years versus 4+/-3 years if culture was negative (p>0.05). The test sensitivity was 77% (CI 95%: 65-86) and its specificity 82% (CI 95%: 75-87), the positive predictive value was 60% (CI 95%: 49-71) and the negative predictive value 91% (CI 95%: 85-95). Antibiotic prescriptions have diminished: no prescription for 70% of pharyngitis and for 93% if cultures were negative.
Conclusion:
The rapid test strip wide use has a strong repercussion on the antibiotics prescription. This test is realist in pediatric emergency unit.
Related Concept Videos
Acute Pharyngitis
Acute pharyngitis is the inflammation of the back of the throat (pharynx), commonly resulting in a sore throat. It is a frequently encountered condition that prompts individuals to seek medical advice.
Classification
Acute pharyngitis can be categorized based on its underlying cause:
Streptococcal Pharyngitis
Pneumonia III: Complications and Assessment
Tonsillitis I: Introduction
Etiology
Three primary contributing factors have been identified.
Rapid Identification of Pathogens
Automated Microbial Diagnostics

