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Updated: Jan 20, 2026

Author Spotlight: Development of a Method for Identifying Small Molecular Antagonists of β2 Integrin Activation
Published on: February 2, 2024
Flow cytometry for drug discovery, receptor pharmacology and high-throughput screening
Larry A Sklar1, Mark B Carter, Bruce S Edwards
1The New Mexico Molecular Libraries Screening Center, Cancer Research and Treatment Center, The University of New Mexico Health Sciences Center, Albuquerque, NM 87131, USA. lsklar@salud.unm.edu
Abstract:
Although flow cytometry is viewed as a mature technology, there have been dramatic advances in analysis capabilities, sorting, sample handling and sensitivity in the past decade. These advances contribute to its application in biological and chemical diversity, sample throughput, high content, and complex systems biology. This article will evaluate the new opportunities for flow cytometry relating to receptor assembly and pharmacology, as well as a range of screening applications.
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