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Updated: Jul 13, 2026

Demonstrating a Multi-drug Resistant Mycobacterium tuberculosis Amplification Microarray
Published on: April 25, 2014
Characterization of Tunisian Mycobacterium tuberculosis rifampin-resistant clinical isolates
Alya Soudani1, Sondess Hadjfredj, Mériem Zribi
1Bacteriology Laboratory, Rabta University Hospital, Tunis, Tunisia. alya_soudani@yahoo.fr
Abstract:
Analysis of the gene encoding the beta-subunit of Mycobacterium tuberculosis RNA polymerase (rpoB) has demonstrated a small region that harbors the mutations most frequently associated with rifampin resistance. In this study, we determined the occurrence of rifampin resistance in 544 Tunisian clinical M. tuberculosis strains isolated in a university hospital between 2004 and 2006 by using the standard-proportion agar method, the INNO-LiPA Rif.TB assay, and DNA sequencing.
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