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Published on: April 26, 2018

p51/p63 Inhibits ultraviolet B-induced apoptosis via Akt activation

E Ogawa1, R Okuyama, S Ikawa

  • 1Department of Dermatology, Tohoku University Graduate School of Medicine, Aoba-ku, Sendai, Japan.

Oncogene
|July 27, 2007
PubMed
Summary

The p53 family member DeltaNp51B protects skin cells from UV-B-induced apoptosis. Its downregulation enhances cell death, while TAp51B expression significantly reduces it, revealing a novel epidermal protection mechanism.

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