Related Experiment Video
Updated: Jul 13, 2026

Anterior High-Resolution Optical Coherence Tomography in the Diagnosis and Therapeutic Monitoring of Ocular Surface Squamous Neoplasia
Published on: August 9, 2024
Spontaneous closure of stage III and IV idiopathic full-thickness macular holes--a two-case report
Zofia Michalewska1, Slawomir Cisiecki, Bartosz Sikorski
1Klinika Okulistyczna Jasne Blonia, Ul. Rojna 90, 91-162, Lódz, Poland. zosia_n@yahoo.com
Background:
To document and study the spontaneous closure of stage III and IV idiopathic full-thickness macular holes by using both optical coherence tomography (Stratus OCT) and spectral optical coherence tomography (SOCT).
Methods:
A two-center, two-case, observational study of stage III and IV macular holes is presented. OCT and SOCT were performed.
Results:
Macular holes spontaneously resolved after 4 to 12 weeks of observation.
Conclusion:
The spontaneous closure of large idiopathic full-thickness stage III and IV macular holes is possible. We suggest that, as long as no smooth oval shape of the macular hole edges appears on the cross-sectional OCT and SOCT scans, there is still a chance for its spontaneous closure.
Related Concept Videos
Angle Closure Glaucoma: Treatment
Glaucoma: Overview
