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Updated: Jul 13, 2026
06:47
Isolation and Analysis of Plasma Lipoproteins by Ultracentrifugation
Published on: January 28, 2021
Tuberous xanthomas in type IIA hyperlipoproteinemia.
K Krishna Mohan1, K Dileep Kumar, B V Ramachandra
1Department of Dermatology, Andhra Medical College, Visakhapatnam, India.
Indian Journal of Dermatology, Venereology and Leprology
|July 28, 2007
Summary
A young girl
Area of Science:
- Dermatology
- Pediatrics
- Lipidology
Background:
- Childhood obesity is a growing concern with potential metabolic complications.
- Xanthomas, lipid deposits in the skin, can indicate underlying lipoprotein disorders.
Purpose of the Study:
- To present a case of tuberous xanthomas in a child with Type IIa hyperlipoproteinemia.
- To highlight the importance of recognizing skin manifestations of lipid disorders in pediatric patients.
Main Methods:
- Clinical examination of skin lesions.
- Diagnostic workup for hyperlipoproteinemia.
Main Results:
- A 4-year-old obese girl presented with multiple yellowish plaques and nodular skin lesions.
- The patient was diagnosed with Type IIa hyperlipoproteinemia, characterized by elevated low-density lipoprotein cholesterol.
Conclusions:
- Tuberous xanthomas can be an early sign of severe hyperlipoproteinemia in children.
- Prompt diagnosis and management of hyperlipoproteinemia are crucial to prevent cardiovascular complications.
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