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Malignant eccrine spiradenoma: an unusual presentation.

S Agarwal¹, R Khanna, N C Arya

¹Department of Surgery and Pathology, Institute of Medical Sciences, Banaras Hindu University Varanasi-221 005, India.

Indian Journal of Dermatology, Venereology and Leprology

|July 28, 2007

Summary

A rare eccrine spiradenoma in a 60-year-old woman transformed malignantly, presenting as an ulcerated groin lesion with satellite nodules and limb swelling. Palliative radiotherapy was administered due to surgical limitations.

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Area of Science:

Dermatology
Oncology
Pathology

Background:

Eccrine spiradenomas are rare benign skin tumors originating from sweat glands.
Malignant transformation of eccrine spiradenoma is exceptionally uncommon, with limited reported cases.
This case presents a unique clinical scenario of advanced malignant eccrine spiradenoma.

Purpose of the Study:

To report an unusual case of malignant eccrine spiradenoma.
To highlight the clinical presentation and diagnostic challenges of this rare entity.
To discuss management strategies for advanced malignant eccrine spiradenoma.

Main Methods:

Clinical case presentation of a 60-year-old woman with a groin lesion.
Histopathological examination to confirm eccrine spiradenoma with malignant transformation.
Assessment of lesion spread, including satellite nodules and lymphoedema.
Evaluation of treatment options, including surgical excision and radiotherapy.

Main Results:

Diagnosis of eccrine spiradenoma with malignant transformation in a satellite nodule.
The lesion presented as a progressively increasing, painless, ulcerated plaque with satellite nodules.
Massive lymphoedema of the right thigh was observed.
Wide surgical excision was not feasible.

Conclusions:

Malignant eccrine spiradenoma is a rare but aggressive neoplasm.
Early diagnosis and appropriate management are crucial, though challenging in advanced cases.
Palliative radiotherapy can be considered when surgical options are limited.