Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Reservoir of Infection01:30

Reservoir of Infection

Infectious diseases arise from intricate interactions between pathogens and their reservoirs. A reservoir of infection refers to the natural habitat where a pathogen lives, grows, and multiplies, serving as a continual source of infection. Reservoirs are broadly classified as either living or nonliving, and each plays a unique role in disease transmission, significantly influencing public health interventions and control strategies.Humans act as reservoirs for a wide array of pathogens,...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

CD28 ligation prevents bacterial toxin-induced septic shock in mice by inducing IL-10 expression.

Journal of immunology (Baltimore, Md. : 1950)·1997
Same author

MR imaging of tubercular spinal arachnoiditis.

AJR. American journal of roentgenology·1997
Same author

Interactions between transvenous nonthoracotomy cardioverter defibrillator systems and permanent transvenous endocardial pacemakers.

Pacing and clinical electrophysiology : PACE·1997
Same author

Role of the carboxyl-terminal region of Porphyromonas gingivalis fimbrillin in binding to salivary proteins.

Infection and immunity·1997
Same author

Phenethyl isothiocyanate modulates clastogenicity of mitomycin C and cyclophosphamide in vivo.

Mutation research·1996
Same author

Expression of functional Porphyromonas gingivalis fimbrillin polypeptide domains on the surface of Streptococcus gordonii.

Applied and environmental microbiology·1996

Related Experiment Video

Updated: Jul 13, 2026

Chronic Salmonella Infection Induced Intestinal Fibrosis
08:40

Chronic Salmonella Infection Induced Intestinal Fibrosis

Published on: September 22, 2019

Mixed Salmonella infection - a case report.

S Joshi1, C Wattal, A Sharma

  • 1Dept. of Clinical Microbiology, Sir Ganga Ram Hospital, Rajinder Nagar, New Delhi - 110 060, India.

Indian Journal of Medical Microbiology
|July 28, 2007
PubMed
Summary

A rare case of enteric fever involved a mixed infection with Salmonella typhi and Salmonella paratyphi A. Bone marrow culture confirmed the dual Salmonella serotype infection, despite negative blood cultures and Widal tests.

More Related Videos

Chronic Salmonella Infected Mouse Model
09:01

Chronic Salmonella Infected Mouse Model

Published on: May 31, 2010

Automated Analysis of Intracellular Phenotypes of Salmonella Using ImageJ
10:39

Automated Analysis of Intracellular Phenotypes of Salmonella Using ImageJ

Published on: August 9, 2022

Related Experiment Videos

Last Updated: Jul 13, 2026

Chronic Salmonella Infection Induced Intestinal Fibrosis
08:40

Chronic Salmonella Infection Induced Intestinal Fibrosis

Published on: September 22, 2019

Chronic Salmonella Infected Mouse Model
09:01

Chronic Salmonella Infected Mouse Model

Published on: May 31, 2010

Automated Analysis of Intracellular Phenotypes of Salmonella Using ImageJ
10:39

Automated Analysis of Intracellular Phenotypes of Salmonella Using ImageJ

Published on: August 9, 2022

Area of Science:

  • Medical Microbiology
  • Infectious Diseases
  • Clinical Diagnostics

Background:

  • Mixed Salmonella serotype infections are infrequently documented in clinical settings.
  • Enteric fever diagnosis can be challenging, often relying on blood cultures and serological tests like the Widal test.
  • Salmonella typhi and Salmonella paratyphi A are common causative agents of enteric fever.

Purpose of the Study:

  • To report an unusual case of mixed Salmonella typhi and Salmonella paratyphi A infection.
  • To highlight the diagnostic utility of bone marrow culture in challenging enteric fever cases.
  • To underscore the importance of considering multiple Salmonella serotypes in enteric fever.

Main Methods:

  • Case report of a patient presenting with symptoms of enteric fever.
  • Blood cultures and Widal test were performed for initial diagnosis.
  • Bone marrow aspirate culture was conducted for definitive pathogen identification.

Main Results:

  • Blood cultures were sterile, and the Widal test yielded negative results.
  • Bone marrow culture successfully isolated both Salmonella typhi and Salmonella paratyphi A.
  • This confirmed a mixed Salmonella infection in the patient.

Conclusions:

  • Bone marrow culture is a valuable diagnostic tool for enteric fever, especially when blood cultures are negative.
  • Mixed Salmonella serotype infections, though rare, should be considered in the differential diagnosis of enteric fever.
  • Accurate identification of all causative Salmonella serotypes is crucial for appropriate patient management and treatment.