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Updated: Jul 13, 2026
Use of In vivo Imaging to Monitor the Progression of Experimental Mouse Cytomegalovirus Infection in Neonates
Published on: July 6, 2013
Cytomegalovirus (AD169) infection in human chondrocyte cell cultures
A M Patti1, A Vulcano, A Gabriele
1Department of Public Health Sciences G. Sanarelli, Sapienza, The University of Rome, Italy. anna.patti@uniroma1.it
Abstract:
Human chondrocytes are susceptible to productive human cytomegalovirus (HCMV, AD169 strain) infection. Infection of chondrocytes resulted in pronounced cytopathic effects including cell rounding and aggregation, fusions, and lysis. Immunohistochemical staining reveals that a portion of chondrocytes expressed antigens reactive to monoclonal antibodies against early HCMV proteins. The interaction of HCMV with cartilage cells may be one key for elucidating the etiopathogenesis of articular diseases.
