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Related Experiment Video

Updated: Jul 13, 2026

The Goeckerman Regimen for the Treatment of Moderate to Severe Psoriasis
11:39

The Goeckerman Regimen for the Treatment of Moderate to Severe Psoriasis

Published on: July 11, 2013

Current and future management of psoriasis.

Alan Menter1, Christopher Em Griffiths2

  • 1Baylor Research Institute and Southwestern Medical School, Dallas, Texas, 75246, USA.

Lancet (London, England)
|July 31, 2007
PubMed
Summary

Effective psoriasis management requires assessing disease extent and considering quality of life. An evidence-based approach guides treatment selection, from topical agents to advanced biological therapies for severe psoriasis.

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Last Updated: Jul 13, 2026

The Goeckerman Regimen for the Treatment of Moderate to Severe Psoriasis
11:39

The Goeckerman Regimen for the Treatment of Moderate to Severe Psoriasis

Published on: July 11, 2013

Area of Science:

  • Dermatology and Immunology
  • Evidence-Based Medicine

Background:

  • Psoriasis management necessitates evaluating disease severity and patient-specific factors.
  • A holistic approach addressing psychosocial disability and quality of life is crucial.
  • Specific disease locations (palms, soles, face, nails) and psoriatic arthritis influence treatment choices.

Purpose of the Study:

  • To outline current evidence-based treatment strategies for psoriasis.
  • To highlight the evolution of psoriasis therapies, including novel biological agents.
  • To emphasize the need for a comprehensive and individualized treatment plan.

Main Methods:

  • Review of current therapeutic options for psoriasis.
  • Analysis of evidence supporting different treatment modalities.
  • Consideration of disease extent, location, and patient comorbidities.

Main Results:

  • Topical agents are primary for mild psoriasis and recalcitrant lesions.
  • Phototherapy suits moderate disease.
  • Systemic therapies, including photochemotherapy, oral agents, and biologics, are vital for severe psoriasis, with biologics revolutionizing care.

Conclusions:

  • An evidence-based, holistic approach is essential for optimal psoriasis management.
  • Current treatments range from topical agents to advanced systemic and biological therapies.
  • Ongoing research aims to develop safe, long-term psoriasis control strategies.