Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Chronic Obstructive Pulmonary Disease-V: Management01:29

Chronic Obstructive Pulmonary Disease-V: Management

3.1K
Managing Chronic Obstructive Pulmonary Disease (COPD) involves a multifaceted approach to reduce symptoms, prevent exacerbations, improve overall health status, and slow disease progression. Key strategies include lifestyle modifications, pharmacotherapy, supportive therapies, and, in some cases, surgery. Here is an overview of the primary COPD management strategies:
Smoking Cessation
3.1K
Drugs Acting on Autonomic Ganglia: Stimulants01:23

Drugs Acting on Autonomic Ganglia: Stimulants

2.0K

Ganglionic stimulants activate NM nicotinic receptors in autonomic ganglia, falling into two categories: nicotine mimetics [e.g., lobeline, dimethylpiperazine, tetramethylammonium] and muscarinic receptor agonists [e.g., muscarine, methacholine]. The first category's action is rapid and blocked by nicotinic receptor antagonists, while the second category's action is delayed and blocked by atropine-like agents. Nicotine, an alkaloid, affects the heart rate by stimulating...
2.0K
CNS Depressants: Alcohol and Nicotine01:27

CNS Depressants: Alcohol and Nicotine

1000
Ethanol, a clear colorless alcohol, has been consumed by humans for millennia, but its effects on the body are far from benign. At lower doses, it induces decreased inhibitions and loquaciousness, leading to its social appeal. However, it can cause severe consequences at higher doses, such as coma and respiratory depression, due to its zero-order elimination kinetics. Chronic ethanol abuse wreaks havoc on multiple organ systems, particularly the CNS and the liver. Abrupt cessation of ethanol...
1000
Drug Dependence01:17

Drug Dependence

1.6K
Medications are typically administered to achieve therapeutic effects. Some drugs can modify an individual's mood and perception, frequently resulting in various enjoyable experiences. However, this can result in drug dependency, a condition marked by continuous drug use despite potential negative consequences. Drug dependency primarily falls into two categories: psychological and physical dependence. Psychological dependence occurs when the pleasurable feelings induced by the drug...
1.6K
COPD: Management Using Bronchodilators and Corticosteroids01:26

COPD: Management Using Bronchodilators and Corticosteroids

705
Chronic obstructive pulmonary isease (COPD) involves a group of progressive lung disorders characterized by persistent airflow limitation and chronic respiratory symptoms. Asthma-COPD Overlap Syndrome (ACOS), encompassing features of both asthma and Chronic obstructive pulmonary disease (COPD), is a group of progressive lung disorders that includes chronic bronchitis, emphysema, and refractory (non-reversible) asthma. ACOS leads to complex clinical presentations that combine the inflammatory...
705
Pulmonary Tuberculosis V01:28

Pulmonary Tuberculosis V

527
Medical management of tuberculosis (TB) patients involves a comprehensive approach that includes diagnosis, treatment, and monitoring. The specific strategies can vary depending on the type of tuberculosis (latent or active), the patient's overall health status, and other considerations.
Latent tuberculosis infection occurs when TB bacteria are present in a person's body, but are not causing illness or symptoms. It is not contagious, and preventive treatment is crucial to avoid the...
527

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Do improvements in clinical practice guidelines alter pregnancy outcomes in asthmatic women? A single-center retrospective cohort study.

The Journal of asthma : official journal of the Association for the Care of Asthma·2023
Same author

Reduction of biological response modifiers in the supernatant of washed paediatric red blood cells.

Vox sanguinis·2016
Same author

Association of early and late maternal smoking during pregnancy with offspring body mass index at 4 to 5 years of age.

Journal of developmental origins of health and disease·2015
Same author

A dose response randomised controlled trial of docosahexaenoic acid (DHA) in preterm infants.

Prostaglandins, leukotrienes, and essential fatty acids·2015
Same author

Expression of eight glucocorticoid receptor isoforms in the human preterm placenta vary with fetal sex and birthweight.

Placenta·2015
Same author

Early red cell transfusion favourably alters cerebral oxygen extraction in very preterm newborns.

Archives of disease in childhood. Fetal and neonatal edition·2015

Related Experiment Video

Updated: Jan 9, 2026

Heat-sensitive Moxibustion as a Traditional Chinese Medicine Therapy for Chronic Obstructive Pulmonary Disease Combined with Insomnia
04:59

Heat-sensitive Moxibustion as a Traditional Chinese Medicine Therapy for Chronic Obstructive Pulmonary Disease Combined with Insomnia

Published on: May 30, 2025

1.2K

Treating cigarette smoking in methadone maintenance clients.

J Story1, M J Stark

  • 1Department of Psychology, University of New Mexico, Albuquerque.

Journal of Psychoactive Drugs
|April 1, 1991
PubMed
Summary

Smoking cessation programs for substance abusers are crucial, as this population has high rates of nicotine dependence. A study found that increasing methadone dosage did not improve abstinence but increased withdrawal symptoms, highlighting the need for tailored relapse prevention strategies.

More Related Videos

A General Method for Evaluating Deep Brain Stimulation Effects on Intravenous Methamphetamine Self-Administration
09:16

A General Method for Evaluating Deep Brain Stimulation Effects on Intravenous Methamphetamine Self-Administration

Published on: January 22, 2016

15.7K
Methods to Evaluate Cytotoxicity and Immunosuppression of Combustible Tobacco Product Preparations
09:25

Methods to Evaluate Cytotoxicity and Immunosuppression of Combustible Tobacco Product Preparations

Published on: January 10, 2015

11.8K

Related Experiment Videos

Last Updated: Jan 9, 2026

Heat-sensitive Moxibustion as a Traditional Chinese Medicine Therapy for Chronic Obstructive Pulmonary Disease Combined with Insomnia
04:59

Heat-sensitive Moxibustion as a Traditional Chinese Medicine Therapy for Chronic Obstructive Pulmonary Disease Combined with Insomnia

Published on: May 30, 2025

1.2K
A General Method for Evaluating Deep Brain Stimulation Effects on Intravenous Methamphetamine Self-Administration
09:16

A General Method for Evaluating Deep Brain Stimulation Effects on Intravenous Methamphetamine Self-Administration

Published on: January 22, 2016

15.7K
Methods to Evaluate Cytotoxicity and Immunosuppression of Combustible Tobacco Product Preparations
09:25

Methods to Evaluate Cytotoxicity and Immunosuppression of Combustible Tobacco Product Preparations

Published on: January 10, 2015

11.8K

Area of Science:

  • Addiction Medicine
  • Behavioral Psychology
  • Clinical Pharmacology

Background:

  • Substance abusers in treatment exhibit significantly higher rates of cigarette smoking compared to the general adult population.
  • There is a notable lack of research on effective smoking-cessation interventions specifically designed for individuals undergoing substance abuse treatment.

Purpose of the Study:

  • To develop and evaluate a behaviorally based smoking-cessation program for clients in methadone maintenance.
  • To assess the efficacy of increasing methadone dosage as a pharmacological aid in smoking cessation for this population.

Main Methods:

  • A double-blind, placebo-controlled study was conducted.
  • Participants were methadone maintenance clients enrolled in a behaviorally based smoking-cessation program.
  • The study compared a group receiving an increased methadone dose against a control group receiving a placebo.

Main Results:

  • No significant differences in reported smoking abstinence rates were observed between the methadone dose increase group and the control group.
  • Subjects receiving a higher methadone dose reported increased nicotine craving and withdrawal symptoms during the initial week of abstinence.
  • Smoking rates were significantly higher in the experimental group compared to the control group throughout the 10-week study.

Conclusions:

  • Increasing methadone dosage is not an effective strategy for smoking cessation in methadone maintenance clients and may exacerbate withdrawal symptoms.
  • Further research is essential to develop effective smoking-cessation programs for methadone clients, emphasizing relapse prevention tailored to their specific needs.
  • Alternative pharmacological strategies, potentially involving nicotine replacement therapy, should be explored for smoking cessation in this population.