Related Experiment Video
Updated: Jul 13, 2026

Social Defeat Stress Model for Adolescent C57BL/6 Male and Female Mice
Published on: March 15, 2024
Interactive effect of substance abuse and depression on adolescent social competence
1Department of Psychology and Neuroscience, Duke University, Durham, NC 27708, USA. sjb21@duke.edu
Abstract:
This study explored the interactive effect of substance abuse and depression on social competence among 106 adolescent inpatients (57% female, 86% Caucasian). Substance abuse and depression were conceptualized using dimensional ratings of illness severity based on adolescent interviews, whereas social competence was conceptualized using parent ratings of adolescent behavior. Cross-sectional analyses revealed that substance abuse and depression had a negative interactive effect on adolescent social competence: Higher severity levels of both dimensions were associated with lower levels of competence than accounted for by the additive effects of the two dimensions. These findings persisted when controlling for gender, race, and other common dimensions of psychopathology. Significant impairment in social competence occurred at subdiagnostic levels of substance abuse when depression severity was high, highlighting the value of assessing outcomes across the full range of severity.
Related Concept Videos
Stress and Mental Health
Individuals with depression often experience challenges in both their personal and professional...
Substance Use Disorders Affecting Sleep
Understanding the concepts of physical dependence,...
Self-Presentation: Self-Monitoring and Self-Handicapping
Influence of Parents and Peers on Identity
Parental Influence on Identity Development
Parents serve as primary guides and managers in an adolescent's life, offering support instrumental in decision-making and personal growth. This guiding role...
Depressive Disorders: Etiology
Biological Factors in Depression
Biological predispositions significantly influence the risk of developing depressive disorders. Genetic studies highlight the role of variations in the serotonin transporter...
Erikson's Theory on Socioemotional Development during Adolescence
