Related Experiment Video
Updated: Jul 13, 2026

New Thrombectomy Technique for Total Portal Vein Thrombosis in Liver Transplantation
Published on: June 27, 2025
Malignant superior vena cava syndrome presenting after trauma
1Royal College Emergency Medicine Program, University of Western Ontario, Canada. lprice3@julian.uwo.ca
A motor vehicle crash patient presented with superior vena cava (SVC) syndrome. Diagnosis revealed T-cell lymphoma encasing the SVC, a rare presentation of malignant SVC syndrome associated with trauma.
Area of Science:
- Oncology
- Thoracic Surgery
- Emergency Medicine
Background:
- Superior vena cava (SVC) syndrome is often caused by malignant diseases like lung cancer and lymphoma.
- Traumatic SVC syndrome is rare, with few reported cases.
- Malignant SVC syndrome typically presents without trauma.
Purpose of the Study:
- To report a unique case of malignant SVC syndrome presenting after a motor vehicle crash.
- To highlight the diagnostic and management challenges in such rare cases.
Main Methods:
- Case report of a 41-year-old male with motor vehicle crash injuries.
- Clinical presentation including dyspnea, cyanosis, and facial swelling.
- Diagnostic workup involving chest tube insertion, thoracotomy, and biopsy.
Main Results:
- The patient presented with symptoms consistent with SVC syndrome.
- Exploratory thoracotomy revealed an extensive tumor encasing the SVC and hilum.
- Biopsy confirmed T-cell lymphoma as the cause.
Conclusions:
- This case represents the first reported instance of malignant SVC syndrome associated with trauma.
- SVC syndrome in trauma patients warrants a high index of suspicion for underlying malignancy.
- Multidisciplinary management is crucial for optimal patient outcomes.
Related Concept Videos
Venous Thrombosis II: Clinical Manifestations and Diagnostic Studies
Veins of Thorax
The azygos vein, positioned just right of the midline and anterior to the vertebral column, begins at the junction of the right ascending lumbar and subcostal veins, terminating in the superior vena cava. This vein drains blood from the right side of the thoracic wall, thoracic viscera, and posterior abdominal wall.
The...
Esophageal Varices-I: Introduction
Venous Thrombosis I: Introduction
Esophageal Varices-II: Clinical Features and Management
In the initial assessment, a thorough review of the patient's medical history is vital to identify risk factors such as liver disease, alcohol abuse, or...
Venous Thrombosis III: Interprofessional Care