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Updated: Jul 13, 2026

In Vivo Assessment of Alveolar Macrophage Efferocytosis Following Ozone Exposure
Published on: October 22, 2019
Toward a biologically significant and usable standard for ozone that will also protect plants
Elena Paoletti1, William J Manning
1IPP-CNR, Via Madonna del Piano 10, I-50019 Sesto Fiorentino, Italy. e.paoletti@ipp.cnr.it
Abstract:
Ozone remains an important phytotoxic air pollutant and is also recognized as a significant greenhouse gas. In North America, Europe, and Asia, incidence of high concentrations is decreasing, but background levels are steadily rising. There is a need to develop a biologically significant and usable standard for ozone. We compare the strengths and weaknesses of concentration-based, exposure-based and threshold-based indices, such as SUM60 and AOT40, and examine the O(3) flux concept. We also present major challenges to the development of an air quality standard for ozone that has both biological significance and practicality in usage.
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