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Pleural Disorders: Types and Brief Description

Pleural Disorders: Types and Brief Description

The pleura is a vital part of the respiratory system. It's a double-layered membrane surrounding the lungs and lining the chest cavity. The two layers of the pleura are:

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Pleural Effusion II: Symptoms and Management

Pleural Effusion II: Symptoms and Management

Pleural Effusion Overview
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Clinical Manifestations:

Pulmonary Tuberculosis III

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Related Experiment Video

Updated: Jul 13, 2026

Generation and Expansion of Primary, Malignant Pleural Mesothelioma Tumor Lines

Generation and Expansion of Primary, Malignant Pleural Mesothelioma Tumor Lines

Published on: April 21, 2022

Intradural pleural malignant mesothelioma.

M Payer¹, T von Briel

¹Spine and Pain Clinic Zürich, Zürich, Switzerland. mpayer@hotmail.com

Acta Neurochirurgica

|July 31, 2007

Summary

Pleural malignant mesothelioma rarely spreads to the spine. This study reviews rare intradural mesothelioma cases and presents a new case of spinal cord involvement.

Area of Science:

Oncology
Neurology
Pathology

Background:

Pleural malignant mesothelioma is a rare cancer originating in the lung's lining.
Tumor progression typically involves local invasion and, rarely, distant spread.
Spinal involvement is exceptionally rare, with intradural locations being even more uncommon.

Observation:

A MEDLINE literature review identified four previously reported cases of intradural mesothelioma.
These cases included one intradural extramedullary and three intramedullary lesions.
A new case involves a patient with pleural mesothelioma spreading intradurally to the T5 spinal cord level.

Findings:

Intradural mesothelioma, while exceedingly rare, represents a distinct pattern of metastatic spread.
The review highlights the varied presentations of intradural mesothelioma, including extramedullary and intramedullary growth.

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Orthotopic Implantation and Peripheral Immune Cell Monitoring in the II-45 Syngeneic Rat Mesothelioma Model

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Generation and Expansion of Primary, Malignant Pleural Mesothelioma Tumor Lines

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Orthotopic Implantation and Peripheral Immune Cell Monitoring in the II-45 Syngeneic Rat Mesothelioma Model

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The reported case adds to the limited understanding of mesothelioma's neuro-invasive potential.

Implications:

This case underscores the importance of considering rare metastatic patterns in mesothelioma patients with neurological symptoms.
Further research into the mechanisms of dural and spinal cord invasion by mesothelioma is warranted.
Accurate diagnosis and understanding of spinal involvement are crucial for patient management and prognosis.