Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

[CO diffusing capacity during continuous negative extra-thoracic pressure].

M Asada1, K Nakayama, K Kaneko

  • 1Department of Anesthesiology, Yokohama City University School of Medicine.

Masui. the Japanese Journal of Anesthesiology
|October 1, 1991
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Sequential treatment with zoledronic acid followed by teriparatide or vice versa increases bone mineral density and bone strength in ovariectomized rats.

Bone reports·2017
Same author

Causal involvement of mammalian-type cryptochrome in the circadian cuticle deposition rhythm in the bean bug Riptortus pedestris.

Insect molecular biology·2011
Same author

A simple, heat-sterilizable artificial diet excluding animal-derived ingredients for adult blowfly, Lucilia sericata.

Medical and veterinary entomology·2009
Same author

Study on the General Anesthesia of Dental Out-patients in Japan: with Particular Reference to Fluothane Nitrous Oxide and Oxygen Anesthesia.

Journal of the American Dental Society of Anesthesiology·2009
Same author

Expression of type V secretory phospholipase A in myocardial remodelling after infarction.

Histopathology·2005
Same author

A phase response curve for circannual rhythm in the varied carpet beetle Anthrenus verbasci.

Journal of comparative physiology. A, Neuroethology, sensory, neural, and behavioral physiology·2005
Same journal

[Significance of Multi-center Respiratory Surgery Perioperative Team Training Including Various Medical Staffs].

Masui. The Japanese journal of anesthesiology·2018
Same journal

[Adherence to and Issues on our Institutional Guidelines on Heparin Administration after Withdrawal of Warfarin before Elective Surgery].

Masui. The Japanese journal of anesthesiology·2018
Same journal

[History of Resuscitation: 3. Development of Resuscitation in the Mid-18 Century-3: Artificial Respiration].

Masui. The Japanese journal of anesthesiology·2018
Same journal

[History of Tracheal Intubation: 4. Use for Cardiopulmonary Resuscitation-2].

Masui. The Japanese journal of anesthesiology·2018
Same journal

[A Case of Well Leg Compartment Syndrome after Robot-assisted Laparoscopic Prostatectomy].

Masui. The Japanese journal of anesthesiology·2018
Same journal

[Anesthetic Management of a Patient with Pulmonary Atresia and Intact Ventricular Septum Accompanying Sinusoidal Communication].

Masui. The Japanese journal of anesthesiology·2018
See all related articles

Continuous negative extra-thoracic pressure (CNETP) does not significantly alter carbon monoxide diffusing capacity (DLCO) in healthy males. This suggests CNETP may not substantially impact pulmonary gas exchange efficiency.

Area of Science:

  • Respiratory Physiology
  • Pulmonary Function Testing

Background:

  • Assessing the impact of external respiratory support on lung function is crucial.
  • Continuous negative extra-thoracic pressure (CNETP) is a non-invasive method to assist breathing.

Purpose of the Study:

  • To compare carbon monoxide diffusing capacity (DLCO) during spontaneous breathing versus CNETP.
  • To evaluate the effect of CNETP on pulmonary gas exchange.

Main Methods:

  • Eight healthy males participated in the study.
  • DLCO was measured during spontaneous breathing and during CNETP with an end-expiratory negative pressure of -20 cmH2O.
  • Pulmonary capillary blood volume was measured in one participant.

Main Results:

Related Experiment Videos

  • Mean DLCO was 33.0 +/- 5.1 ml.min-1.mmHg-1 during spontaneous breathing and 33.5 +/- 4.5 ml.min-1.mmHg-1 during CNETP.
  • No significant difference in DLCO was observed between the two conditions (P < 0.05).
  • Pulmonary capillary blood volume showed a non-significant increase during CNETP.

    • Conclusions:

    • CNETP does not significantly alter pulmonary diffusing capacity for carbon monoxide in healthy individuals.
    • The impact of CNETP-induced changes in diffusing capacity on oxygenation improvement appears minimal.
    • Further research may be needed to explore potential benefits in specific patient populations.