Related Experiment Video
Updated: Jul 13, 2026

Using Multi-fluorinated Bile Acids and In Vivo Magnetic Resonance Imaging to Measure Bile Acid Transport
Published on: November 27, 2016
Value of cine MRI for better visualization of the proximal small bowel in normal individuals
Michael R Torkzad1, Roberto Vargas, Chikako Tanaka
1Department of Diagnostic Radiology, Karolinska University Hospital Solna, S-171 76, Stockholm, Sweden.
Abstract:
While enteroclysis seems to be the most efficacious method in achieving bowel distension, enterographic methods have become widespread due to the unpleasantness of enteroclysis and the radiation involved with positioning the catheter. Cine images in MRI can be done without radiation. Our aim is to see if and how cine MR imaging can improve visualization of bowel loops by capturing them while distended. Ten healthy individuals were asked to drink up to 2,000 ml of an oral solution made locally over a 60-min period. Then they underwent MRI using coronal balanced fast field echo (b-FFE) covering small bowel loops. If the initial exam revealed collapsed bowel loops an additional 50 mg of erythromycine was given intravenously with the subject still in the scanner and then cine imaging was performed. The degree of distension of different segments of the small bowel was measured before and after cine imaging and compared. The distension score was significantly higher after addition of the cine images as well, being only significant for depiction of the duodenum and jejunum. Our preliminary study suggests that cine MRI can give better image depiction of the proximal small bowel in healthy volunteers, perhaps circumventing the need for enteroclysis in some cases. There is a need for validation of these results in patients with small bowel disease.
Insights
Cine MRI imaging enhances small bowel visualization by capturing distended loops without radiation. This preliminary study suggests it may reduce the need for enteroclysis in some cases.
Area of Science:
- Radiology
- Gastroenterology
- Medical Imaging
Background:
- Enteroclysis is effective for bowel distension but is invasive and involves radiation.
- Enterographic methods are common alternatives due to enteroclysis's drawbacks.
- Magnetic Resonance Imaging (MRI) offers radiation-free imaging possibilities.
Purpose of the Study:
- To evaluate if cine MR imaging improves visualization of distended small bowel loops.
- To assess the potential of cine MRI as an alternative to enteroclysis.
Main Methods:
- Ten healthy volunteers consumed 2,000 ml of oral solution over 60 minutes.
- Standard MRI with coronal balanced fast field echo (b-FFE) was performed.
- Intravenous erythromycin and subsequent cine imaging were administered if initial loops were collapsed.
Main Results:
- Bowel distension scores significantly increased after cine imaging.
- Improved visualization was significant for the duodenum and jejunum.
- Cine MRI enhanced the depiction of proximal small bowel loops.
Conclusions:
- Cine MRI shows promise for improved visualization of the proximal small bowel in healthy individuals.
- This technique may potentially circumvent the need for enteroclysis in select cases.
- Further validation in patients with small bowel disease is warranted.
Related Concept Videos
Imaging Studies III: Gastrointestinal Motility Studies and Virtual Colonoscopy
Radionuclide Testing
Radionuclide testing is a sophisticated medical technique for assessing gastrointestinal motility. It focuses on gastric emptying and colonic transit time. Radioactive markers track the movement of food through the digestive system, providing insights into gastrointestinal disorders.
In gastric emptying studies, a meal's liquid and solid...
Magnetic Resonance Imaging
Imaging Studies for Cardiovascular System IV: CMRI
Lower GI Series: Barium Enema
Procedure Details
The examination begins by inserting a lubricated rectal tube into the patient's rectum to administer a radiopaque barium solution. The barium flow is carefully...
Imaging Studies IV: Magnetic Resonance Imaging
Imaging Studies I: CT and MRI
Description of the Procedures
Computed Tomography (CT) scan:
Computed Tomography (CT) scans use X-ray technology to generate detailed images of bones, organs, and tissues. During the scan, the patient lies on a moving table...
