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Related Experiment Videos

Central serous chorioretinopathy.

Maria Wang1, Inger Christine Munch, Pascal W Hasler

  • 1Department of Ophthalmology, Glostrup Hospital, University of Copenhagen, Copenhagen, Denmark.

Acta Ophthalmologica
|July 31, 2007
PubMed
Summary
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Central serous chorioretinopathy (CSC) is a retinal condition causing fluid buildup under the retina, often linked to stress. Treatments like photocoagulation or photodynamic therapy may be considered if vision doesn't improve spontaneously.

Area of Science:

  • Ophthalmology
  • Retinal Diseases
  • Chorioretinopathy

Background:

  • Central serous chorioretinopathy (CSC) is a retinal condition affecting the neurosensory retina and retinal pigment epithelium (RPE).
  • It commonly affects middle-aged men, presenting with blurred vision, central scotoma, micropsia, and metamorphopsia, often unilaterally.
  • Psychosocial stress and hypercortisolism are potential triggers for CSC.

Purpose of the Study:

  • To summarize the characteristics, diagnosis, and management of Central serous chorioretinopathy (CSC).
  • To discuss spontaneous resolution, treatment options, and therapeutic targets in CSC management.

Main Methods:

  • Ophthalmoscopic examination reveals RPE lesions and neurosensory retinal detachment.
  • Diagnostic signs range from focal RPE lesions with fluid elevation to larger areas of RPE depigmentation.

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  • Subretinal fluid may contain granular or fibrinous material.

    • Main Results:

    • CSC often resolves spontaneously within months, but prolonged detachment can lead to photoreceptor atrophy.
    • Focal photocoagulation is effective for acute CSC, while photodynamic therapy is used for chronic CSC.
    • Differentiating chronic CSC from choroidal neovascularization is crucial for appropriate management.

    Conclusions:

    • Early counseling regarding stress and glucocorticoids is essential for CSC patients.
    • Treatment selection should prioritize cases unlikely to resolve spontaneously to achieve reattachment within 4 months.
    • Management of chronic CSC may allow continuation of systemic glucocorticoid therapy.