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Four-year recurrence rate and prognosis of the apical ballooning syndrome
Ahmad A Elesber1, Abhiram Prasad, Ryan J Lennon
1Division of Cardiovascular Diseases, Mayo Clinic, Rochester, Minnesota 55905, USA.
Insights
Apical ballooning syndrome (ABS) has an 11.4% recurrence rate within 4 years. Chest pain recurrence is common, but long-term survival for ABS patients is similar to the general population.
Area of Science:
- Cardiology
- Internal Medicine
Background:
- Apical ballooning syndrome (ABS) is an acute cardiac condition with unknown causes and prognosis.
- ABS is also known as stress-induced cardiomyopathy or takotsubo cardiomyopathy.
Purpose of the Study:
- To evaluate the long-term prognosis of patients diagnosed with apical ballooning syndrome (ABS).
Main Methods:
- Retrospective analysis of 100 unselected patients with confirmed ABS via angiography.
- Tracking of ABS recurrences and patient mortality over a mean follow-up period.
Main Results:
- Over a mean follow-up of 4.4 years, 11.4% of patients experienced ABS recurrence within the first 4 years.
- 31% of patients reported recurrent chest pain; 17 patients died during follow-up.
- No significant difference in overall or cardiovascular survival was observed compared to age- and gender-matched populations.
Conclusions:
- The 4-year recurrence rate for apical ballooning syndrome is 11.4%.
- Recurrent chest pain is a frequent symptom post-ABS diagnosis.
- Long-term survival for ABS patients is comparable to the general population.
Objectives:
This study sought to assess the long-term prognosis of patients with apical ballooning syndrome (ABS).
Background:
Apical ballooning syndrome is a recently described acute cardiac syndrome of uncertain etiology and prognosis.
Methods:
We retrospectively identified 100 unselected patients with a confirmed diagnosis of ABS by angiography. Recurrences of ABS and mortality were recorded.
Results:
Over a mean follow-up of 4.4 +/- 4.6 years, 31 patients continued to have episodes of chest pain and 10 patients had recurrence of ABS, for a recurrence rate of 11.4% over the first 4 years. Seventeen patients died in 4.7 +/- 4.8 years of follow-up. There was no difference in survival or in cardiovascular survival to an age- and gender-matched population.
Conclusions:
The recurrence rate for ABS was 11.4% over 4 years after initial presentation. Recurrence of chest pain is common. Four-year survival was not different from that in an age-matched and gender-matched population.
