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Chronic constipation in hemiplegic patients.

F Bracci1, D Badiali, P Pezzotti

  • 1Dipartimento Scienze Cliniche (2(0) Cl. Medica), Policlinico "Umberto I" V.le del Policlinico 155, Rome 00161, Italy. danilo.badiali@uniroma1.it.

World Journal of Gastroenterology
|August 1, 2007
PubMed
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Chronic constipation is a common outcome for hemiplegic patients following a stroke, independent of physical inactivity. Certain medications like nitrates and antithrombotics may increase constipation risk.

Area of Science:

  • Neurology
  • Gastroenterology

Background:

  • Bowel dysfunction is a common issue in patients with hemiplegia.
  • Understanding the contributing factors is crucial for effective management.

Purpose of the Study:

  • To determine the prevalence of bowel dysfunction in hemiplegic patients.
  • To investigate the relationship between bowel dysfunction and neurological lesion site, physical immobilization, and pharmacotherapy.

Main Methods:

  • A comparative study involving 90 hemiplegic patients and 81 orthopedic patients.
  • Assessment using a questionnaire on bowel habits and the Adapted Patient Evaluation Conference System for mobility.
  • Analysis of pharmacotherapy including nitrates, ACE inhibitors, calcium antagonists, anticoagulants, antithrombotics, antidepressants, and anti-epileptics.

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Main Results:

  • Constipation was significantly more frequent in hemiplegic patients (OR=5.36).
  • Hemiplegics reported increased straining, reduced urge, incomplete evacuation, and higher laxative use.
  • Constipation was independently associated with hemiplegia and positively associated with nitrates and antithrombotics.

Conclusions:

  • Chronic constipation affects approximately 30% of stabilized hemiplegic patients post-stroke.
  • Constipation onset is independent of brain lesion location and physical inactivity.
  • Nitrates and antithrombotics are potential independent risk factors for constipation in this population.