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Updated: Jul 13, 2026

Full-root Aortic Valve Replacement by Stentless Aortic Xenografts in Patients with Small Aortic Roots
Published on: May 21, 2017
[Aortic valve replacement in octogenarians with severe aortic stenosis. Experience in a series of consecutive
David Calvo1, Iñigo Lozano, Juan C Llosa
1Area Clínica del Corazón, Hospital Universitario Central de Asturias, Oviedo, Asturias, España. Davidcalvo-307@hotmail.com
Insights
Aortic valve replacement surgery is effective and safe for patients aged 80 and older with severe aortic stenosis, showing good long-term survival and low complication rates. Key mortality predictors include creatinine levels, emergency surgery, and reintervention for bleeding.
Area of Science:
- Cardiovascular Surgery
- Geriatric Cardiology
- Valvular Heart Disease
Context:
- Increasing life expectancy leads to more cases of severe aortic stenosis in octogenarians.
- Percutaneous aortic valve prostheses are emerging as an alternative treatment option.
- Evaluating current surgical outcomes in elderly patients is crucial.
Purpose:
- To assess the effectiveness and safety of aortic valve replacement (AVR) in patients aged 80 years and older with severe aortic stenosis.
- To analyze short-term and long-term outcomes, including survival rates and complications.
- To identify predictors of mortality in this patient cohort.
Summary:
- 104 out of 137 octogenarians (75.9%) with severe aortic stenosis underwent AVR.
- Perioperative complications were low (myocardial infarction 2.9%, stroke 5.8%, pacemaker 5.8%), with 30-day mortality at 3.8%.
- Long-term survival rates were favorable, with 6-year survival at 60%. Predictors of mortality included elevated creatinine, emergency surgery, and reintervention for bleeding. 76.3% of patients improved functionally (NYHA class I-IV).
Impact:
- Aortic valve replacement is a viable and successful treatment for severe aortic stenosis in octogenarians.
- The study provides valuable data on surgical outcomes in an aging population.
- Findings support AVR as a beneficial intervention, despite identified mortality predictors.
Introduction And Objectives:
Greater life-expectancy has led to an increase in the incidence of severe aortic stenosis, which accounts for a significant proportion of the workload of cardiology departments. With the imminent arrival of percutaneous aortic valve prostheses, it is important to know how effective surgery currently is in octogenarians.
Methods:
The study included all patients aged >or=80 years with severe aortic stenosis who underwent cardiac catheterization prior to aortic valve replacement between May 1996 and May 2006. The percentage of patients who underwent surgery, outcomes at 30 days, long-term survival, and predictors of mortality were analyzed.
Results:
Of the 137 patients evaluated, 104 (75.9%) underwent surgery, while 33 did not due to a low ejection fraction or severe chronic bronchitis, or because the patient's family did not give consent. The patients' mean age was 81.7 (1.5) years, 61.5% were female, 18.4% had diabetes, 7.8% had had a previous infarction, and 32.7% had coronary disease. Three patients (2.9%) had a perioperative myocardial infarction, six (5.8%) had a stroke, and six (5.8%) had a permanent pacemaker. Four patients (3.8%) died during the first 30 days. The survival rates at 1, 2, 3, 4, 5 and 6 years were 90 (2.9), 81 (4.2), 78 (4.8), 75 (5.3), 65 (7.2) and 60 (8.2)%, respectively. The following predictors of long-term mortality were identified: creatinine level, emergency surgery, and reintervention because of bleeding. Some 76.3% of patients remained in New York Heart Association functional class I-IV.
Conclusions:
Aortic valve replacement can be performed successfully in patients aged >or=80 years with severe aortic stenosis; the complication rate was low, and the survival rate and long-term results were good. Predictors of mortality in this series were the creatinine level, emergency surgery, and reintervention because of bleeding.
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