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Sporotrichosis in Manipur: report of two cases

K H Ranjana1, A Chakrabarti, M Kulachandra

  • 1Department of Medical Microbiology, Postgraduate Institute of Medical Education &Research, Chandigarh -160012, India.

Indian Journal of Dermatology, Venereology and Leprology
|August 1, 2007
PubMed

Insights

Two cases of lymphocutaneous sporotrichosis caused by Sporothrix schenckii were identified in Manipur. Both patients recovered after treatment with potassium iodide, marking the first reported instances in the region.

Area of Science:

  • Medical Mycology
  • Infectious Diseases

Background:

  • Sporotrichosis is a fungal infection typically caused by Sporothrix schenckii.
  • Lymphocutaneous sporotrichosis presents a distinct clinical manifestation of the disease.

Purpose of the Study:

  • To report the first confirmed cases of lymphocutaneous sporotrichosis in Manipur.
  • To document the diagnostic methods and successful treatment of these cases.

Main Methods:

  • Isolation and identification of Sporothrix schenckii from patient pus samples.
  • Confirmation through in vitro mycelial to yeast conversion at 37°C.
  • Assessment of pathogenicity in a mouse model.

Main Results:

  • Sporothrix schenckii was successfully isolated and identified in both patients.
  • One patient had a history of injury from fermented fish bone (Ngari).
  • Both patients showed successful recovery following oral potassium iodide treatment.

Conclusions:

  • These represent the first authentic cases of sporotrichosis documented in Manipur.
  • Oral potassium iodide is an effective treatment for lymphocutaneous sporotrichosis.
  • Highlights the importance of considering sporotrichosis in endemic areas with relevant exposure history.

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