Search research articles

ABOUT JoVE

Overview Leadership Blog JoVE Help Center

AUTHORS

Publishing Process Editorial Board Scope & Policies Peer Review FAQ Submit

LIBRARIANS

Testimonials Subscriptions Access Resources Library Advisory Board FAQ

RESEARCH

JoVE Journal Methods Collections JoVE Encyclopedia of Experiments Archive

EDUCATION

JoVE Core JoVE Business JoVE Science Education JoVE Lab Manual Faculty Resource Center Faculty Site

Terms & Conditions of Use

Related Concept Videos

Skin Diseases and Disorders

Skin Diseases and Disorders

Skin is the first line of defense and encounters a variety of microbes. Some pathogenic strains are often the cause of a broad range of infections of the skin and other body systems. These conditions can affect people of all ages and may have different causes, including genetic factors, infections, autoimmune reactions, environmental factors, and lifestyle choices.
Gram-positive Staphylococcus spp. and Streptococcus spp. are responsible for many of the most common skin infections. However, many...

Changes in Skin Color: Clinical Perspectives

Changes in Skin Color: Clinical Perspectives

The first thing a clinician sees is the skin, so the examination of the skin should be part of any thorough physical examination. Most skin disorders are relatively benign, but a few, including melanomas, can be fatal if untreated. A couple of the more noticeable disorders, albinism and vitiligo, affect the appearance of the skin and its accessory organs.
Albinism
Albinism is a genetic disorder that affects (completely or partially) the coloring of skin, hair, and eyes. The defect is primarily...

Pigmentation

Pigmentation

The color of the skin is influenced by a number of pigments, including melanin, carotene, and hemoglobin. Recall that melanin is produced by cells called melanocytes, which are found scattered throughout the stratum basale of the epidermis. The melanin is transferred to the keratinocytes via melanosomes.
Melanin occurs in two primary forms: eumelanin that provides black and brown pigment and pheomelanin that provides red color. Dark-skinned individuals produce more melanin than those with pale...

Autoimmune Disorders

Autoimmune Disorders

Autoimmune diseases are a group of disorders in which the body's immune system mistakenly attacks its own cells, tissues, and organs. This results from an overactive immune response against substances and tissues normally present in the body. Let's delve into the concept and mechanism of autoimmune diseases from an immune system point of view, explore different causes and examples of such diseases, and discuss potential solutions.
Concept and Mechanism of Autoimmune Diseases
The immune system...

Reticular Dermis

Reticular Dermis

The papillary and reticular dermis are the two layers of the dermis. They are made of connective tissue with fibers of collagen extending from one to the other, making the border between the two somewhat indistinct. The dermal papillae extending into the epidermis belong to the papillary layer, whereas the dense collagen fiber bundles below belong to the reticular layer.
Reticular Layer
Underlying the papillary layer is the much thicker reticular layer, composed of dense, irregular connective...

EPS and iPS Cells in Disease Research

EPS and iPS Cells in Disease Research

Embryonic and induced pluripotent stem cells are excellent models for disease research because of their ability to self-renew and differentiate into most cell types. Somatic cells from a patient are isolated and reprogrammed into induced pluripotent stem cells or iPSCs. These iPSCs are later differentiated into the desired cell type, which mirrors the diseased cell of the patient. In this way, disease models have been created for investigating diseases such as Down syndrome, type I diabetes,...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by

Same author

Bitter orange (<i>Citrus aurantium</i> L.) extract subchronic 90-day safety study in rats.

Toxicology reports·2017

Same author

Citrus aurantium (bitter orange) extract: Safety assessment by acute and 14-day oral toxicity studies in rats and the Ames Test for mutagenicity.

Regulatory toxicology and pharmacology : RTP·2017

Same author

Papuloerythroderma of ofuji.

Indian journal of dermatology, venereology and leprology·2017

Same author

Pyoderma gangrenosum masquerading as Donovanosis.

Indian journal of sexually transmitted diseases and AIDS·2015

Same author

A clinico-histopathological study of lupus vulgaris: A 3 year experience at a tertiary care centre.

Indian dermatology online journal·2014

Same author

Retrospective analysis of fixed drug eruptions among patients attending a tertiary care center in Southern India.

Indian journal of dermatology, venereology and leprology·2014

Search research articles

Related Experiment Videos

Vitiligo and psoriasis: coexistence with colocalization.

A C Inamadar¹, V V Sampagavi, S B Athanikar

¹Department of Dermatology, Venereology & Leprosy BLDEA's SBMP Medical College, Bijapur-586 103, India.

Indian Journal of Dermatology, Venereology and Leprology

|August 1, 2007

Summary

This case report details a 20-year-old male with co-existing vitiligo and psoriasis, noting shared lesions. The study discusses the clinical heterogeneity and offers new conclusions on these dermatological conditions.

Related Experiment Videos

Area of Science:

Dermatology
Immunodermatology

Background:

Vitiligo and psoriasis are distinct autoimmune skin conditions.
Co-occurrence of vitiligo and psoriasis is uncommon.
Understanding shared or distinct pathogenic mechanisms is crucial.

Purpose of the Study:

To report a rare case of a 20-year-old male patient with concurrent vitiligo and psoriasis.
To analyze the clinical presentation and co-localization of lesions.
To discuss the clinical heterogeneity and potential implications for understanding both diseases.

Main Methods:

Case report of a single patient.
Clinical observation and documentation of dermatological conditions.
Review of existing literature on co-existing vitiligo and psoriasis.

Main Results:

A 20-year-old male presented with both vitiligo and psoriasis.
Lesions of both conditions were observed to co-exist and, in some areas, co-habit the same skin sites.
The clinical presentation exhibited heterogeneity, suggesting complex interactions.

Conclusions:

The co-existence of vitiligo and psoriasis in a young male patient highlights the complex interplay between different autoimmune dermatoses.
Shared lesions suggest potential common triggers or overlapping inflammatory pathways.
Further research is warranted to elucidate the underlying mechanisms and clinical significance of this co-occurrence.