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Updated: Jul 13, 2026

Implantation of Osmotic Pumps and Induction of Stress to Establish a Symptomatic, Pharmacological Mouse Model for DYT/PARK-ATP1A3 Dystonia
Published on: September 12, 2020
[Standardized load test in the diagnostics of neurocirculatory dystonia]
Abstract:
Thirty-five men with neurocirculatory dystonia (NCD) aged 24.4 +/- 1.8 and 22 practically healthy men of comparable age were examined. All the patients underwent standard load veloergometric test by step-up technique until submaximum heart rate was achieved. The study found significant increase in myocardial oxygen consumption both at rest and during physical exercise. The author offers quantitative criteria that allow for objective evaluation of disturbances in the regulatory systems that provide response to measured physical load and thus contribute to clinical diagnostics of NCD.
