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[Magnesium deficit in climacteric women]

N V Izmozherova, A A Popov, M I Fominykh

    Klinicheskaia Meditsina
    |August 2, 2007
    PubMed

    The aim of the study was to assess the prevalence of magnesium deficit (MD) in climacteric women and its effect on the severity of climacteric syndrome (CS). This cross-sectional study included 165 women with typical CS manifestations. Patients with arterial hypertension were excluded. Blood levels of magnesium and calcium as well as lipid exchange variables in blood serum were studied. The degree of CS was determined using modified menopausal index (MMI). MD was revealed in 62.4% of the patients. The frequency of obesity and excessive body mass was significantly higher in MD women vs. women whose magnesium levels were normal (chi2 = 4.477; p = 0.034). MD was associated with a higher risk of peripheral bone fractures (OR = 2.28; 95% CI 1.06-4.93). Normal magnesium levels were found in less than 50% of women with clinical manifestations of DM. MD was associated with a higher frequency of abdominal obesity and bone fractures of extremities.

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