An unusual case of a central nervous system tumor presenting as a chief complaint of depression
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Updated: Jul 13, 2026

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Published on: July 5, 2021
Nicolas M Oreskovic1, Christopher G Strother, Lara M Zibners
1Department of Pediatrics, Mount Sinai School of Medicine, New York, NY 10029, USA.
Abstract:
Patients presenting to the emergency department with a psychiatric chief complaint often undergo a medical clearance examination. There is much debate in the literature as to the value of routine laboratory and other diagnostic studies in the initial evaluation of these patients. We report on a patient presenting to the pediatric emergency department with a chief complaint of depression who ultimately was found to have diabetes insipidus and a primary intracranial germ cell tumor. Although a rare outcome to a relatively common scenario in the emergency department, this case underscores the value of a detailed history, careful physical examination, and consideration of laboratory and other diagnostic studies in patients presenting to the emergency department for psychiatric evaluation.
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