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Evaluation of Left Ventricular Structure and Function using 3D Echocardiography
06:34

Evaluation of Left Ventricular Structure and Function using 3D Echocardiography

Published on: October 28, 2020

Prognostic value of tissue Doppler-derived ventricular asynchrony in patients with left bundle branch block but not

Rodolfo Citro1, Antonello D'Andrea, Marco Mariano Patella

  • 1U.O. UTIC-Cardiologia, San Luca Hospital, Vallo della Lucania, Salerno, Italy. rodolfocitro@tele2.it

Journal of Cardiovascular Medicine (Hagerstown, Md.)
|August 2, 2007
PubMed

Insights

Tissue Doppler echocardiography-derived interventricular asynchrony is a significant predictor of cardiac events in patients with left bundle branch block (LBBB). This finding aids in assessing prognosis for major cardiac events within two years.

Area of Science:

  • Cardiology
  • Echocardiography
  • Heart Failure Research

Background:

  • Left bundle branch block (LBBB) can lead to ventricular dyssynchrony.
  • Assessing the prognostic value of this dyssynchrony in non-advanced heart failure patients is crucial.

Purpose of the Study:

  • To evaluate the prognostic significance of tissue Doppler echocardiography (TDE)-derived ventricular asynchrony.
  • To determine if TDE can predict major cardiac events in LBBB patients without advanced heart failure.

Main Methods:

  • Fifty-five LBBB patients (NYHA class II) underwent standard Doppler and TDE.
  • Measured precontraction time (PCTm) in LV and RV segments to calculate intraventricular and interventricular delays (IntraV-del, InterV-del).

Main Results:

  • Interventricular delay (InterV-del) showed a significant inverse relationship with ejection fraction (EF).
  • During 26 months follow-up, 41% of patients experienced cardiac events (worsening heart failure or cardiac death).
  • InterV-del and age were independent predictors of mortality; a cutoff of 100 ms for InterV-del predicted cardiac events.

Conclusions:

  • TDE-derived interventricular asynchrony is a valuable prognostic indicator.
  • It predicts major cardiac events in LBBB patients with preserved ejection fraction.
  • This method aids in risk stratification for LBBB patients.
Abstract

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