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Predictors and outcome of gastrointestinal complications in patients undergoing cardiac surgery
Farzan Filsoufi1, Parwis B Rahmanian, Javier G Castillo
1Department of Cardiothoracic Surgery, Mount Sinai School of Medicine, New York, NY 10029, USA. farzan.filsoufi@mountsinai.org
Insights
Gastrointestinal complications following cardiac surgery are rare (<1%), but associated with increased mortality. Identifying high-risk patients and implementing preventive measures are crucial for better outcomes.
Area of Science:
- Cardiology
- Gastroenterology
- Surgical Outcomes
Background:
- Gastrointestinal complications (GICs) like ischemia and hemorrhage are rare but severe after cardiac surgery.
- Evolving patient profiles necessitate re-evaluation of GIC incidence and risk factors.
Purpose of the Study:
- To determine the incidence of GICs after cardiac surgery.
- To identify independent predictors of GICs in this patient population.
Main Methods:
- Retrospective analysis of prospectively collected data from 4819 cardiac surgery patients (1998-2004).
- Comparison of patients with GICs to the general patient population.
- Multivariate analysis to identify independent predictors of GICs.
Main Results:
- GICs occurred in 1.1% of patients, primarily intestinal ischemia (59%) and hemorrhage (41%).
- Incidence decreased over the study period and varied by procedure type (e.g., CABG/valve highest, CABG lowest).
- Independent predictors included advanced age, myocardial infarction, CHF, hemodynamic instability, prolonged bypass time, PVD, renal, and hepatic failure.
Conclusions:
- Gastrointestinal complications after cardiac surgery are infrequent (<1%) in contemporary series.
- Preventive measures and intraoperative advancements are key to reducing GIC incidence.
- Identifying high-risk patients allows for targeted perioperative monitoring to mitigate GICs.
Objective:
To determine the incidence and independent predictors of gastrointestinal complications (GICs) following cardiac surgery.
Summary Background Data:
Gastrointestinal ischemia and hemorrhage represent a rare but devastating complication following heart surgery. The profile of patients referred for cardiac surgery has changed during the last decade, questioning the validity of previously reported incidence and risk factors.
Methods:
We retrospectively analyzed prospectively collected data from 4819 patients undergoing cardiac surgery between 1998 and 2004. Patients with GICs were compared with the entire patient population. Study endpoints were mortality, postoperative morbidities, and long-term survival.
Results:
GICs occurred in 51 (1.1%) patients. Etiologies were intestinal ischemia (n = 30; 59%) and hemorrhage (n = 21; 41%). The incidence decreased during the study period (1998-2001: 1.3%, 2002-2004: 0.7%; P = 0.04). The incidence per type of procedure was as follows: coronary artery bypass grafting (CABG)/valve (2.4%), aortic surgery (1.7%), valve surgery (1.0%), and CABG (0.5%; P = 0.001). Multivariate analysis revealed age (odds ratio [OR] = 2.1), myocardial infarction (OR = 2.5), CHF (OR = 2.4), hemodynamic instability (OR = 2.8), cardiopulmonary bypass time >120 minutes (OR = 6.2), peripheral vascular disease (OR = 2.2), renal (OR = 3.2), and hepatic failure (OR = 10.8) as independent predictors of GICs. The overall hospital mortality among patients with GICs was 33%. Long-term survival was significantly decreased in patients with GICs compared with the control group.
Conclusions:
Gastrointestinal complications following cardiac surgery remain rare with an incidence <1% in a contemporary series. The key to a lower incidence of GICs lies in systematic application of preventive measures and new advances in intraoperative management. Identification of independent risk factors would facilitate the determination of patients who would benefit from additional perioperative monitoring. Future resources should therefore be redirected to mitigate GICs in high-risk patients.
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