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Related Experiment Video

Updated: Jul 13, 2026

Conjunctival Commensal Isolation and Identification in Mice

Conjunctival Commensal Isolation and Identification in Mice

Published on: May 1, 2021

Alcaligenes xylosoxidans conjunctivitis.

Ryan Rush¹, Miles Friedlander

¹Department of Ophthalmology, Tulane University, New Orleans, LA, USA. ryanbradfordrush21@hotmail.com

|August 2, 2007

Summary

This case report details a chronic conjunctivitis in a healthy woman caused by Alcaligenes xylosoxidans. Topical Timentin successfully treated this rare external ocular infection.

Area of Science:

Ophthalmology
Infectious Diseases
Microbiology

Background:

Chronic conjunctivitis can be caused by various pathogens.
Identifying the causative agent is crucial for effective treatment.

Observation:

A previously healthy 47-year-old woman presented with a 3-month history of left eye purulent discharge and irritation.
Initial treatments with bacitracin and olopatadine were ineffective.

Findings:

Conjunctival culture identified Alcaligenes xylosoxidans, an unusual cause of conjunctivitis.
The isolate was resistant to common antibiotic classes including aminoglycosides, fluoroquinolones, and cephalosporins.
Topical Timentin 2% achieved complete resolution of the infection after 14 days.

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Last Updated: Jul 13, 2026

Conjunctival Commensal Isolation and Identification in Mice

Conjunctival Commensal Isolation and Identification in Mice

Published on: May 1, 2021

Nasolacrimal Lavage as a Treatment for Ocular Surface Toxic Soup Syndrome

Nasolacrimal Lavage as a Treatment for Ocular Surface Toxic Soup Syndrome

Published on: April 25, 2025

Implications:

This is the first reported case of external ocular infection and isolated conjunctivitis caused by Alcaligenes xylosoxidans in an immunocompetent host.
Alcaligenes xylosoxidans should be considered a potential pathogen in chronic conjunctivitis, even in patients without apparent risk factors.
This case highlights the importance of microbiological investigation for recalcitrant ocular infections.