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Related Experiment Video

Updated: Jul 13, 2026

Design of Cecal Ligation and Puncture and Intranasal Infection Dual Model of Sepsis-Induced Immunosuppression

Design of Cecal Ligation and Puncture and Intranasal Infection Dual Model of Sepsis-Induced Immunosuppression

Published on: June 15, 2019

[Sepsis in the sphenoiditis patient].

Krzysztof Preś¹, Marek Bochnia, Beata Rostkowska-Nadolska

¹Katedra i Klinika Otolaryngologii AM we Wrocławiu.

Otolaryngologia Polska = the Polish Otolaryngology

|August 3, 2007

Summary

Sepsis from isolated sphenoiditis is rare but serious. Prompt diagnosis and combined surgical and antibiotic treatment led to complete recovery in a 61-year-old woman.

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Last Updated: Jul 13, 2026

Design of Cecal Ligation and Puncture and Intranasal Infection Dual Model of Sepsis-Induced Immunosuppression

Design of Cecal Ligation and Puncture and Intranasal Infection Dual Model of Sepsis-Induced Immunosuppression

Published on: June 15, 2019

Area of Science:

Otolaryngology
Infectious Diseases
Medical Case Reports

Background:

Presents a rare case of sepsis originating from isolated sphenoiditis.
Highlights the diagnostic challenges associated with uncommon infections.

Observation:

A 61-year-old woman presented with prolonged fever, leukocytosis, and weight loss.
Initial diagnostics failed to identify systemic or neoplastic diseases.
NMR revealed sphenoid sinus shadowing, leading to surgical intervention.

Findings:

Surgical drainage of the sphenoid sinus yielded Staphylococcus aureus.
The pathogen was susceptible to Vancomycin and Tienam.
Combined surgical treatment and targeted antibiotic therapy resulted in complete symptom resolution.

Implications:

Emphasizes that isolated sphenoiditis, though rare, poses significant diagnostic and therapeutic challenges.
Underscores the potential for life-threatening complications due to delayed diagnosis.
Suggests a multidisciplinary approach for managing complex sinonasal infections.