[Hyposensitization and antihistamines in the treatment of bronchial and allergic rhinitis]

The control of symptoms in patients with allergic rhinitis and bronchial asthma can not be always attained with hyposensitization. This may be achieved with more success with additional treatment with H1 antagonists of histamine receptors. By hyposensitization statistically significant decrease of the total IgE was achieved. Contrary to this, in cases in which the symptoms could not be controlled with hyposensitization, only antihistamines were additionally administered, no significant decrease of IgE took place. These were, probably, more severe cases in which the symptoms could not be controlled with the hyposensitization only. No significant effect on the values of blood eosinophiles was registered with hyposensitization or additional administration of antihistamines.